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Laboratory Test Information

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CBC (Complete Blood Count, American Association for Clinical Chemistry)

Abbr Test Medline Plus ("Normal") Group Health Explanations
SOURCES: || MedlinePlus
Male Female
RBC Red Blood Count 4.7-6.1 mill cells/mcl 4.2-5.4 3.9-5.6 Red blood cell (RBC) count is a count of the actual number of red blood cells per volume of blood. Both increases and decreases can point to abnormal conditions. Decreased with anemia; increased when too many made and with fluid loss due to diarrhea, dehydration, burns
WBC White Blood Count
4,500 - 10.000
4,000 - 10,800 White blood cell (WBC) count is a count of the actual number of white blood cells per volume of blood. Both increases and decreases can be significant. May be increased with infections, inflammation, cancer, leukemia; decreased with some medications (such as methotrexate), some autoimmune conditions, some severe infections, bone marrow failure, and congenital marrow aplasia (marrow doesn't develop normally)
Hgb Hemoglobin 13.8-17.2 gm/dL 12.1-15.1 gm/dL 11.4-17.0 gm/dL Mirrors RBC results; Hemoglobin measures the amount of oxygen-carrying protein in the blood.
Hct Hematocrit 40.7-50.3% 36.1-44.3% 38-50% Mirrors RBC results; Hematocrit measures the percentage of red blood cells in a given volume of whole blood.
MCV Mean Corpuscular Volume 80-95 femtoliter 80-98 Increased with B12 and Folate deficiency; decreased with iron deficiency and thalassemia
MCH Mean Corpuscular Hemoglobin 27-31 pg/cell 27-34 Mirrors MCV results
MCHC Mean Corpuscular Hemoglobin Concentration 32 to 36 gm/dL 33-37 May be decreased when MCV is decreased; increases limited to amount of Hgb that will fit inside a RBC
RDW RBC Distribution Width 8.0-18.5 Increased RDW indicates mixed population of RBCs; immature RBCs tend to be larger
Platelet Platelet Count 140-450 10*3 "Platelets, or thrombocytes are small, irregularly shaped clear cell fragments.... The average lifespan of a platelet is normally just 5 to 9 days. Platelets are a natural source of growth factors..." (Wikipedia) If the number of platelets is too low, excessive bleeding can occur. However, if the number of platelets is too high, blood clots can form (thrombosis), which may obstruct blood vessels and result in such events as a stroke, myocardial infarction, pulmonary embolism or the blockage of blood vessels to other parts of the body, such as the extremities of the arms or legs.
The platelet count is the number of platelets in a given volume of blood. Both increases and decreases can point to abnormal conditions of excess bleeding or clotting. Mean platelet volume (MPV) is a machine-calculated measurement of the average size of your platelets. New platelets are larger, and an increased MPV occurs when increased numbers of platelets are being produced. MPV gives your doctor information about platelet production in your bone marrow.
Decreased or increased with conditions that affect platelet production; decreased when greater numbers used, as with bleeding; decreased with some inherited disorders (such as Wiskott-Aldrich, Bernard-Soulier), with Systemic lupus erythematosus, pernicious anemia, hypersplenism (spleen takes too many out of circulation), leukemia, and chemotherapy
(cells/mcL = cells per microliter; gm/dL = grams per deciliter; pg/cell = picograms per cell)
Creatinine 0.7-1.3 mg/dL 0.6-1.1 mg/dL 0.5-1.4 mg/dL "Creatinine is a breakdown product of creatine, which is an important part of muscle." "Creatinine can also be measured with a urine test" (Source: MedlinePlus || Creatinine Tests)
GFR Glomerular Filtration Rate 90-120 mL/min/1.73sqm 60-100 GFR - is the best test to measure your level of kidney function and determine your stage of kidney disease. Your doctor can calculate it from the results of your blood creatinine test, your age, race, gender and other factors. The earlier kidney disease is detected, the better the chance of slowing or stopping its progression. "Your GFR tells how much kidney function you have. It may be estimated from your blood level of creatinine. If your GFR falls below 30 you will need to see a kidney disease specialist (called a nephrologist), Your kidney doctor will speak to you about treatments for kidney failure like dialysis or kidney transplant. A GFR below 15 indicates that you need to start one of these treatments." (Source: National Kidney Foundation)

"Levels below 60 mL/min/1.73 m2 for 3 or more months are a sign of chronic kidney disease." "According to the National Kidney Foundation, normal results range from 90 - 120 mL/min/1.73sqm. Older people will have lower normal GFR levels, because GFR decreases with age." (Source: MedlinePlus)

AST aspartate aminotransferase 10 to 34 IU/L 6-35 ... is an enzyme found in high amounts in heart muscle and liver and muscle cells. It is also found in lesser amounts in other tissues. This test is mainly done along with other tests (such as ALT, ALP, and bilirubin) to diagnose and monitor liver disease. [MedlinePlus]
CRP & hs-CRP (highly sensitive) C-Reactive Protein
"C" stands for "capsular"
CRP: 0-1.0 mg/dL or less than 10 mg/L (SI units)

hs-CRP levels:
Less than 1.0 mg/L: High-sensitivity C-reactive protein (hs-CRP) levels Less than 1.0 mg/LZ: Lowest risk
1.0 to 3.0 mg/L: Average risk
More than 3.0 mg/L: Highest risk
Source: WebMD

A C-reactive protein (CRP) test is "a blood test that measures the amount of a protein called C-reactive protein in your blood. C-reactive protein measures general levels of inflammation in your body. High levels of CRP are caused by infections and many long-term diseases. But a CRP test cannot show where the inflammation is located or what is causing it. Other tests are needed to find the cause and location of the inflammation... A special type of CRP test, the high-sensitivity CRP test (hs-CRP), may be done to find out if you have an increased chance of having a sudden heart problem, such as a heart attack. " [ WebMed]

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